Cisplatin and hypokalemia

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August undefined, 2024

WebSep 20, 2024 · The most common adverse reactions in the two trials (≥25% with difference between arms of >5% compared to cisplatin alone) were vomiting, nausea, decreased hemoglobin, hypernatremia, and... WebDec 9, 2024 · When hypokalemia is secondary to tumor activity, treating the cancer is necessary, in addition to symptomatic therapy for hypokalemia, in order to prevent the recurrence of symptoms. Patients with carcinoid syndrome should receive somatostatin analog in order to inhibiting hormonal hyper-secretion and improve symptoms [ 136 ] .

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WebApr 12, 2024 · AKI-related cisplatin may also be associated with tubulopathies, such as Fanconi-like syndrome, hypomagnesemia, salt-loosing syndrome and distal renal tubular acidosis . Tubular dysfunction is characterized by electrolyte disorders such as hyponatremia, hypokalemia and hypomagnesemia. WebAug 1, 2004 · Nephrotoxicity after cisplatin administration usually manifests as increased serum creatinine and blood urea nitrogen (BUN) levels, as well as electrolyte … dickson advanced analytics

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Web21 hours ago · The EARLY-MYO-BC trial is the first to explore the cardiac impacts of pyrotinib in the neoadjuvant setting for this patient population. Patients are currently … WebApr 1, 2024 · Triple disorder with metabolic alkalosis, metabolic acidosis, and respiratory alkalosis Compensated metabolic alkalosis Analyzing an acid-base disturbance is a 5-step process. Step 1: Look at the pH. Our patient’s arterial pH was 7.55, which, being higher than 7.45, shows a state of alkalemia. WebHypokalemia may develop with furosemide, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids, ACTH, licorice in large amounts, or prolonged use of laxatives. ... There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly. In ... cittern wikipedia

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DRUG NAME: Cisplatin - BC Cancer

WebDigitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects. All patients receiving LASIX therapy should be observed for these signs or symptoms of fluid or ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as ... WebCisplatin is a common cause of hypomagnesemia and hypokalemia due to renal magnesium (Mg) and potassium (K) losses. Magnesium plays an important role in the … dickson adventist schoolWebMar 24, 2024 · Case 1: A case of hyponatremia following cisplatin chemotherapy A 64 year-old man with small cell lung cancer was treated with cisplatin chemotherapy with etoposide and concurrent chest radiotherapy. Serum sodium was 137 mmol/L prior to initiation of chemotherapy. citt forms

"WebMar 4, 2024 · He completed three cycles of neoadjuvant dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin (dd-MVAC), which was complicated by multiple gastrointestinal (GI) symptoms of nausea, vomiting, resultant hypokalemia, and cytopenia, but he was able to successfully undergo definitive robot-assisted laparoscopic radical … " - Cisplatin and hypokalemia

Cisplatin and hypokalemia

WebKey Points. When evaluating hypokalemia, use the history to explore possible losses (renal vs. GI), shifts (pH, insulin, etc.), and intake. Get a full medication history. Then use the … Webactivity of cisplatin [see Clinical Pharmacology (12.1), Clinical Studies (14)]. • Administer PEDMARK 6 hours after completion of a cisplatin infusion. • For multiday cisplatin regimens, administer PEDMARK 6 hours after completion of each cisplatin infusion and at least 10 hours before the next cisplatin infusion. Do not

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WebMar 25, 2024 · The most common laboratory findings include: hyponatremia, hyperkalemia, and anemia [ 4 ]. Hydrocortisone is the mainstay of treatment, and fludrocortisone is added to replace mineralocorticoid deficiency. Usually, hydrocortisone doses are divided into two or three doses, with the highest dose in the morning to mimic the circadian rhythm. WebApr 10, 2024 · Med-Surg Nursing. Hypocalcemia is when there are low levels of calcium in the blood. Calcium is an electrolyte that plays a vital role in many bodily functions, including muscle contraction, nerve transmission, and bone formation. Various factors, including nutritional deficiencies, medications, and underlying medical conditions, can all lead ...

WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative … WebDec 17, 2024 · Hypokalemia is defined as a serum or plasma potassium that is less than the normal value. Most reference laboratories establish the lower pediatric limit of normal …

WebApr 15, 2024 · Eventually, nephrotoxicity complicated by hypomagnesaemia was confirmed, and cisplatin-induced nephrotoxicity led to the final diagnosis of a familial form of … WebMar 5, 2014 · Cisplatin is a coordinate metal complex with significant antineoplastic activity, and its side effects include acute and chronic renal insufficiency, renal magnesium …

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WebHypomagnesemia generally resolves with cessation of therapy. Cisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin. dickson ag dry feedWebThe Radiation Therapy Oncology Group launched a phase III trial to test the hypothesis that adding cetuximab to the radiation-cisplatin platform improves progression-free survival (PFS).Patients and methodsEligible patients with stage III or IV HNC were randomly assigned to receive radiation and cisplatin without (arm A) or with (arm B) cetuximab. dickson alexander chevrolet dickson advisoryWebFirst-line multiagent chemotherapy comprises doxorubicin, cisplatin, and high-dose methotrexate (MAP regimen) . ... Regarding toxicity, rash and hypokalemia was the most common grade 3 adverse event, and one death from end organ failure was reported that was possibly related to the drug. cit the forestWebOther (less than 2%): Anaphylaxis, bronchospasm, tachycardia, angina, hypokalemia, electrocardiographic alterations, vascular occlusive events, and grand mal seizures. Except for bronchospasm and anaphylaxis, the relationship to ondansetron is unclear. ... More than 90% of patients receiving a cisplatin dose greater than or equal to 50 mg/m 2 ... dickson ag big headWebMedications that cause RTA include Cisplatin and Amphotericin B. You may have hypokalemia from a loss of body fluids due to excessive vomiting, diarrhea, or … dickson aerial sprayingWeb• Cisplatin is a common cause of hypomagnesemia and hypokalemia due to renal magnesium (Mg) and potassium (K) losses. Magnesium plays an important role in the maintenance of intracellular K. An unrecognized and untreated Mg depletion can lead to a refractory K repletion. cit the box