Foxm1 birc5
WebDec 12, 2024 · BIRC5 downregulation inhibits cell growth but promotes apoptosis in breast cancer cells 46. Moreover, BIRC5 silencing induces DNA double-strand breaks and impairs DNA repair capacity 47. BIRC5 is transcriptionally modulated by FOXM1, and overexpression of FOXM1 and BIRC5 is related to drug resistance and unfavorable … WebBIRC5,CCNB1,FOXM1: Beta-cell proliferation, but not neogenesis, following 60% partial pancreatectomy is impaired in the absence of FoxM1. 18714155: BIRC5,TOP2A: Characterization of 5-fluorouracil-resistant cholangiocarcinoma cell …
Foxm1 birc5
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WebApr 23, 2024 · Using cytoHubba software, 10 genes (FN1, CXCL8, CXCL10, SPP1, FOXM1, AURKA, ISG15, PLAUR, TPX2, and BIRC5) were selected as hub genes according to the connectivity degree (Table 3). According to Figure S2a, the hub genes could interact with each other and they might be the driven-genes in OSCC development and progression. WebMay 7, 2024 · FOXM1 also upregulates BIRC5 (also known as survivin), a gene critical for mitotic spindle checkpoint integrity and for antiapoptotic activity ( 8 – 10 ). However, the … FOXM1 was required not only for cell proliferation in response to mitogens, … FOXM1 was required not only for cell proliferation in response to mitogens, …
WebOct 28, 2024 · In keeping with the known binding of FOXM1 to DNA sequences termed cell cycle gene homology regions (CHR) via its interaction with the MuvB complex several of the most highly correlated genes were regulators or markers of cell cycle progression (CCNB2, MKI67, TPX2 & BIRC5), suggesting that FOXM1 may serve to sustain post … WebMay 25, 2024 · The most downregulated gene in FOXM1 RNAi was BIRC5, which encodes the well-established pro-survival factor known as Survivin. The most upregulated gene was BMF, ...
WebFig. 6 FOXM1 acts as a downstream effecter of FZD5. A CCLE database was interrogated for FZD5, FOXM1, BRCA1, and BIRC5 expression. Correlation between two genes in a total of 57 breast cancer cell lines was analyzed by Pearson statistics. B FOXM1, BRCA1, and BIRC5 expression in MDA-MB-231 cells was detected by Western blot. WebFurthermore, we present a molecular pathway for MD/PD SC, including VEGFA, FOXM1, TPX2, BIRC5 and TOP2A, all significantly upregulated and directly interacting with TP53. Conclusions: We have identified 21 mRNAs differentially expressed (p<0.01) between MD/PD SC, SBOT and SNO. Thirteen were differentially expressed in MD/PD SC, …
WebMar 21, 2024 · FOXM1 (Forkhead Box M1) is a Protein Coding gene. Diseases associated with FOXM1 include Hepatocellular Carcinoma and Protein C Deficiency.Among its related pathways are Loss of Nlp from mitotic centrosomes and Cell Cycle, Mitotic.Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity … java xa transaction managerWebMay 24, 2024 · Hello, I Really need some help. Posted about my SAB listing a few weeks ago about not showing up in search only when you entered the exact name. I pretty … javax.batch.runtime.jobinstanceWebMar 14, 2024 · The AURKA-PLK1-FOXM1 axis interacts with β-catenin, which supports the resistance of BCR-ABL+ leukemic stem cells to tyrosine kinase inhibitors (86, 95–97). PLK1 physically interacts with β-catenin and phosphorylates it on Ser718 in the M phase of the cell cycle, indicating an important M-phase specific function of β-catenin such as the ... javaxbWebSep 12, 2024 · EO2040 is a new immune therapy based on FOXM1 & BIRC5 mimics and will start a Phase 2 trial in Q3 2024 in patients suffering from colorectal cancer with ctDNA-defined, minimal residual disease ... javax api mavenWebMar 21, 2024 · Higher expression of MKI67, PCNA, TOP2A, BIRC5, FOXM1 and lower expression of KRT19, KRT20, CDX2 were observed in HMMR (RHAMM)+CD44+ cells (Figure 2F). Taken together, we identified an HMMR (RHAMM)+ CD44 + proliferative subpopulation using organoids that recapitulated the intratumoral heterogeneity of … java xamlWebThe Township of Fawn Creek is located in Montgomery County, Kansas, United States. The place is catalogued as Civil by the U.S. Board on Geographic Names and its elevation … kuroko no basket kawaharaWebJun 15, 2015 · FOXM1 is highly expressed in human liver and lung cancer. (A) FOXM1 levels obtained from Oncomine analysis of the Roessler et al. microarray showed … javax.activation java 11