WebAnti Cancer Activity of the Plant Nothapodytes Nimmoniana Sep 2009 - May 2010. This project was based on finding out the anti cancer activity of the plant Nothapodytes Nimmoniana. Using various ... WebNothapodytes dimorpha (Craib) Sleum. synonym. Nothapodytes foetida (Wight) Sleumer. synonym. Nothapodytes gardneriana (Miers) A.J.G.H. Kostermans. synonym. Premna nimmoniana Grah. synonym. Stemonurus foetidus Wight.
Patterns of accumulation of camptothecin, an anti-cancer
WebNothapodytes nimmoniana (Icacinaceae), a small tree distributed in the Indian subcontinent. Because of the enormous demand for the chemical worldwide, there has been an indiscriminate extraction of the trees from many parts of India, especially from the Western Ghats, a mega-diversity forest range along the western coast of India. WebAn endophytic fungus producing camptothecin (CPT) was isolated from the leaf of Nothapodytes nimmoniana (Sri Lanka), and culture conditions were optimised to enhance the yield of CPT. The TLC, HPLC-PDA, LC-MS/MS and spectroscopic data were used to identify and quantify CPT. Solvent extraction (chloroform: methanol 4:1 v/v) of submerged … imput bloqueado power apps
Biotechnology of camptothecin production in Nothapodytes nimmoniana …
WebDec 10, 2014 · In recent years, Nothapodytes nimmoniana (Graham) Mabb., one of the medicinally important tree species distributed in the Western Ghats has become a major source of DNA topoisomerase inhibiting anti-cancer drug, Camptothecine (CPT) , one of the alkaloids sought after by the pharmaceutical industries around the world . The global ... WebNothapodytes nimmoniana (J. Graham) Mabberly is an endangered medicinal woody plant native to the South Asian continent (Isah, 2024). The plant synthesizes monoterpene indole alkaloid Camptothecin (CPT) which is well-studied for its antitumor properties. The CPT is effective against breast, lung, and uterine cervical cancer (Potmesil, 1986 ... Webplant products. Nothapodytes foetida (also known as Mappia foetida or Nothapodytes nimmoniana) is an average size tree belonging to family Icacinaceae. It is distributed in … imputation strategy